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DC Field | Value | Language |
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dc.contributor.author | Sitkar, A. D. | - |
dc.contributor.author | Derbak, M. A. | - |
dc.contributor.author | Rostoka, L. M. | - |
dc.contributor.author | Hanych, O. T. | - |
dc.contributor.author | Ганич, Оксана Тарасівна | - |
dc.date.accessioned | 2023-05-24T10:28:23Z | - |
dc.date.available | 2023-05-24T10:28:23Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | Association between serum zinc, copper and selenium levels and the degree of liver damage in patients with chronic hepatitis C. / Andrii D. Sitkar, Mariya A. Derbak, Larysa M. Rostoka, Oksana T. Hanych. // Wiad Lek. — 2022. — № 76(10). — P. 2392-2396. | uk |
dc.identifier.uri | https://dspace.uzhnu.edu.ua/jspui/handle/lib/51770 | - |
dc.description.abstract | HCV 1b genotype was detected in all patients. The proportion of patients with a high viral load was 32%, with a low viral load – 68%. In 19% of patients, the level of Zn was below normal, and the levels of Cu and Se were within the reference values. The proportion of patients without fibrosis was 32%, 16% had minimal fibrosis, 40% had moderate fibrosis, 8% had progressive fibrosis, and 3% had severe fibrosis. 68% of patients had active inflammation of various degrees, liver steatosis – 65%, non-alcoholic steatohepatitis – 48%, inflammation caused by alcohol consumption was absent. No statistically significant difference was found in serum trace element levels and viral load (p>0.05). A weak negative correlation between the level of Zn and the degree of fibrosis (ρ=-0.340, p=0.007) and a negligible negative correlation between the level of Zn and inflammation activity (ρ=-0.286, p=0.024) were revealed. Patients with fibrosis grade ≥F2 had lower Zn levels compared to patients with fibrosis ≤F1 (0.607 (0.540, 0.691) mg/l vs. 0.716 (0.593, 0.875) mg/l, p=0.01), and when comparing there was no difference in Cu and Se levels (р>0.05). | uk |
dc.language.iso | en | uk |
dc.publisher | ALUNA Publishing House | uk |
dc.subject | chronic hepatitis C | uk |
dc.subject | trace elements | uk |
dc.subject | liver fibrosis | uk |
dc.subject | zinc | uk |
dc.subject | FibroMax | uk |
dc.title | Association between serum zinc, copper аnd selenium levels and the degree of liver damage in patients with chronic hepatitis c | uk |
dc.type | Text | uk |
dc.pubType | Стаття | uk |
Appears in Collections: | Наукові публікації кафедри факультетської терапії |
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Association between serum zinc, copper and selenium levels and the degree of.pdf | 194.05 kB | Adobe PDF | View/Open |
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