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DC Field | Value | Language |
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dc.contributor.author | Дербак, Марія Антонівна | - |
dc.contributor.author | Buchok, O. V. | - |
dc.contributor.author | Ганич, Тарас Михайлович | - |
dc.contributor.author | Рівіс, Марія Василівна | - |
dc.contributor.author | Лазур, Яна Василівна | - |
dc.contributor.author | Поляк-Товт, Вікторія Михайлівна | - |
dc.contributor.author | Derbak, M. A. | - |
dc.contributor.author | Ganich, T. M. | - |
dc.contributor.author | Rivis, M. V. | - |
dc.contributor.author | Lazur, Y. V. | - |
dc.contributor.author | Polyak-Tovt, V. M. | - |
dc.contributor.author | Timashev, V. V. | - |
dc.date.accessioned | 2024-02-21T08:01:46Z | - |
dc.date.available | 2024-02-21T08:01:46Z | - |
dc.date.issued | 2023 | - |
dc.identifier.citation | Derbak M. A. Peculiarities of the functional state of the liver in patients with chronic hepatitis c in the presence of chronic pancreatitis / M. A. Derbak, O. V. Buchok, T. M. Ganich, M. V. Rivis, Y. V. Lazur, V. M. Polyak-Tovt, V. V. Timashev. — Wiadomości Lekarskie Medical Advances. VOLUME LXXVI, ISSUE 11. 2023. — P. 2359-2364 | uk |
dc.identifier.uri | https://dspace.uzhnu.edu.ua/jspui/handle/lib/58978 | - |
dc.description.abstract | The aim: To study the features of the functional state of the liver in patients with chronic hepatitis C (CHC) in the presence of CP, depending on the enzymatic activity of the pancreas. Materials and methods: 72 patients were under observation: 52 with CHC and CP with exocrine secretory insufficiency (EI) of the pancreas and 20 - with CHC and CP without EI. In all patients, the degree of liver fibrosis, levels of aminotransferases, total bilirubin, gamma-glutamyltransferase, albumin, stool coproscopy and pancreatic fecal elastase-1 (FE-1) were determined. Results: It was revealed that in patients with CHC combined with CP+EI of the pancreas, higher activity of the necroinflammatory process and deeper stages of liver fibrosis is more often noted than in patients with preserved exocrine function of the pancreas. A statistically significant association was established between the degree of liver fibrosis and the presence of EI of the pancreas (p=0.03), namely, in patients with CHC and CP with EI of the pancreas, the degree of fibrosis F2-4 was 2.8 times more frequent. Also, higher levels of aminotransferases and lower levels of albumin were noted in this group of patients than in patients with CHC and CP with preserved exocrine function of the pancreatic gland. Conclusions: In patients with CHC combined with CP+EI of the pancreas, higher levels of fibrosis and necroinflammatory activity of the liver are more often detected, as well as a tendency to lower albumin levels, than in patients with CHC and CP without EI. | uk |
dc.language.iso | en | uk |
dc.publisher | Wiadomości Lekarskie Medical Advances | uk |
dc.subject | chronic hepatitis C | uk |
dc.subject | chronic pancreatitis | uk |
dc.subject | liver fibrosis | uk |
dc.subject | exocrine insufficiency | uk |
dc.subject | fecal elastase-1 | uk |
dc.title | Peculiarities of the functional state of the liver in patients with chronic hepatitis c in the presence of chronic pancreatitis | uk |
dc.type | Text | uk |
dc.pubType | Стаття | uk |
Appears in Collections: | Наукові публікації кафедри госпітальної терапії |
Files in This Item:
File | Description | Size | Format | |
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PECULIARITIES OF THE FUNCTIONAL STATE OF THE LIVER IN.pdf | 441.85 kB | Adobe PDF | View/Open |
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