Протистресорні ефекти даларгіну в щурів за умов хронічного стресу

Abstract

Dalargin antistress efficacy was investigated in rats in condition of chronic stress modelling. Chronic stress was shown to increase the rats' aggressive behaviour as well as stress-responsible organs weight decreasing and lymphopoetic organs weight increasing. This condition was followed bу the suprarenal glands cortical and cerebral layers width increasing also. Dalargin using in rats with chronic stress modelling resulted in the mentioned effects normalization. The data obtained are discussed from the point of view of dalargin recommendations to bе involved into the stress-induced components of the diseases complex pharmacological correction.