Стан показників перекисного окислення ліпідів та антиоксидантної системи у хворих на гемобластози

Abstract

102 patients with haemoblastosis and 36 persons of control group have been examined bу us. Acute lymphoblast leucoses has been diagnosed in 22 patients and 15 patients had the diagnosis of myeloblasts leucoses, 21 patients had chronic myeloleucosis and 44 patients had lympholeucosis. Having analyzed the interrelation of change indexes of lipid peroxidation, antioxidant system we established their inverse proportional connection in patients іІІ with acute and chronic leucoses. The obtained results indicated the interconditionality between intensive processing of free radical lipid oxydation and low content of exogenous antioxidants in patients with acute and chronic leucoses. Antioxidant level rising in an organism in the conditions of the given pathology improves regulating in lipid peroxidation processing and in this way indicates on the important role of including of antioxidant system into the complex therapy.