Endometrial hyperplasia as a consequence of mixed urogenital infections

Abstract

Aim: Investigation of hyperproliferative diseases of the female genital organs as a consequence of mixed urogenital infections. Materials and Methods: The study included 56 women of reproductive age who experienced discomfort in the external genital area in the form of excessive vaginal discharge and/or unpleasant odour of the discharge, itching in the external genital area (main group). The control group consisted of 30 somatically and gynaecologically healthy patients. Results: The following complaints were noted in mixed infections: increased amount of vaginal discharge (28 women / 50% of the main group), unpleasant odour of discharge (19 women / 34%), less frequently - itching (10 women / 18%), burning (11 women / 20%), pain during intercourse (8 women / 14%), digestive tract disorders - bloating and irregular bowel movements (13 women / 23%). Two or more complaints were noted in 29 patients (52% of the main group). The microscopy revealed a small number or complete absence of lactobacilli, abundant polymorphic gram-negative and gram-positive bacillus and coccusmicroflora, and the presence of ‘key cells’. Conclusions: Taking into account the information described above, it can be noted that mixed urogenital infections affect the pathogenesis of endometrial hyperplastic processes.