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Title: | Regio- and stereoselective synthesis of [1,3] thiazolo[3,2-b][1,2,4]triazol-7-ium salts via electrophilic heterocyclization of 3-Spropargylthio-4Н-1,2,4-triazoles and their antimicrobial activity |
Other Titles: | Regio- and stereoselective synthesis of [1,3] thiazolo[3,2-b][1,2,4]triazol-7-ium salts via electrophilic heterocyclization and their antimicrobial activity |
Authors: | Сливка, Михайло Васильович Король, Наталія Іванівна Пантьо, Валерій Валерійович Баумер, Вячеслав Миколайович Лендєл, Василь Георгійович |
Keywords: | electrophilic cyclization; halogen; regioselectivity; stereoselectivity; tellurium tetrahalogenides; [1,3] thiazolo[3,2-b][1,2,4]triazol-7-ium salts |
Issue Date: | 28-Apr-2017 |
Publisher: | De Gruyter |
Citation: | Mikhailo Slivka, Nataliya Korol, Valerij Pantyo, Vjacheslav Baumer and Vasil Lendel. // Heterocycl. Commun. 2017. Issue 2, Pages 111–117. Scopus. CC Database. |
Series/Report no.: | Наукова стаття;2017-01 |
Abstract: | A procedure for the preparation of the title salts via regioselective halocyclization of 3-S-propargylthio-4Н- 1,2,4-triazoles is reported. Stereoselectivity of electrophilic heterocyclization depends on the nature of the electrophilic reagent: bromination is better than iodobromination and iodination. The heterocyclization with tellurium tetrahalogenides leads to the formation of a mixture of geometric isomers of the salts. Their structure was confirmed by 1H NMR, 13C NMR, НМВС and single crystal X-ray diffraction analysis. |
Type: | Text |
Publication type: | Стаття |
URI: | https://dspace.uzhnu.edu.ua/jspui/handle/lib/15776 |
Appears in Collections: | Наукові публікації кафедри органічної хімії |
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