Вивчення та можливості лікування гелікобактеріозу в родинах хворих з ураженням гастродуоденальної зони

Abstract

SUMMARY Study and opportunity of helicobacteriosis treatment in families of the patients with gastroduodenal disorders Kolesnyk P.O., Chоpey I.V., Dolgosh M.Ju., Rubtsova Je.I., Knishev V.I., Drozd S.I., Rishko V.V., Kharitonova Z.B., Kuzmik V.M. The main theme of the article contains analysis of intrafamilial clustering and transmission which is implicated as a major route for acquisition of Helicobacter pylori infection. The occurrence of digestive disorders in household members of the patients with chronic gastritis and duodenal ulcer disease families was observed by clinical and instrumental investigation. It proves the high risk of digestive disorders, associated with Helicobacter pylori, in the household members of the index patients. The results of the analysis prove the necessity of all-family eradication treatment in order to avoid reinfection, intrafamilial clustering and transmission of Helicobacter pylori infection. It can also reduce the risk of digestive disorders, associated with Helicobacter pylori, in the household members of the index patients. The household members and the index patients treatment by the schedule list (which included omeprasole, augmentine, cyprofloxacine during 7 days) caused high eradication effect observed by invasive tests and was mostly always accompanied by changes in Ig G titres. Key words: duodenal ulcer disease, chronic gastritis, Helicobacter pylori, family helicobacteriosis, reinfection, eradication, intrafamilial clustering