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Title: | DYNAMICS OF GASTRIN LEVEL IN PATIENTS WITH DIABETES MELLITUS 2 TYPE AND CHRONIC GASTRITIS AFTER HELICOBACTER PYLORI ERADICATION THERAPY |
Authors: | Sirchak, Yelyzaveta Patskun, Silviya Bedey, Nelli |
Keywords: | diabetes mellitus 2 type, chronic gastritis, helicobacter pylori, saccharomyces boulardii |
Issue Date: | Nov-2020 |
Publisher: | Wiadomości Lekarskie |
Series/Report no.: | VOLUME LXXIII, ISSUE 11; |
Abstract: | The aim: To study the gastrin level dynamics in patients with diabetes mellitus (DM) 2 type and chronic gastritis (CG) on the background of antihelicobacter therapy (AHT). Materials and methods: 60 patients with DM type 2 and HP-associated CG underwent examination. Patients were divided into two groups of 30 patients each: group 1 included patients who received only standard AHT, group 2 – patients who in addition to standard AHT received the drug SB (Normagut, company Mega) 2 capsules 2 times/day. Results: According to our study results yeast SB, not only increase the HP eradication rate but together with the standard AHT contribute to the serum gastrin reduction, which is a gastric acid stimulator, which in turn leads to an improvement in the CG clinical course. Conclusions: Patients with DM type 2 and CG associated with HP should include yeast SB to standard AHT as they reduce side effects from this treatment (by an average of 20%), increase the eradication frequency (by 10%), and also lead to significant decrease in serum gastrin (up to 82.15 ± 2.47 pg/ml).A decrease in serum gastrin levels in patients with HP-associated CG and DM type 2 leads to an improvement in the clinical course of the diseases, namely a decrease in nausea, diarrhea, abdominal pain, and discomfort incidence. |
Type: | Text |
Publication type: | Стаття |
URI: | https://dspace.uzhnu.edu.ua/jspui/handle/lib/37541 |
Appears in Collections: | Наукові публікації кафедри фізіології та патофізіології |
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