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Title: | Метаболіти вітаміну D у хворих із хронічними вірусними гепатитами і цирозами печінки |
Other Titles: | Vitamin D metabolites in patients with chronic viral hepatitis and liver cirrhosis |
Authors: | Митник, З. М. |
Keywords: | chronic liver hepatitis, liver cirrhosis, vitamin D metabolites, osteoporosis |
Issue Date: | 2003 |
Publisher: | ПП "Ліра" |
Citation: | Митник, З. М. Метаболіти вітаміну D у хворих із хронічними вірусними гепатитами і цирозами печінки / З. М. Митник // Науковий вісник Ужгородського університету : серія: Медицина / редкол.: А.С. Головацький (гол. ред.), К.С. Волков, О.М. Ганич та ін. – Ужгород : ПП "Ліра", 2003. – Вип. 19. – С. 146–149. – Бібліогр.: с. 149 (8 назв). – Рез. англ. |
Abstract: | In 72 patients with chronic liver disorders (37 patients with chronic viral hepatitis and 35 patients with liver ciттhosis) serum contents of basic vitamin D metabolites - 25-hydroxyvitamin D and 1,25-dihydroxycholecalciferal were studied. It was established, that in patients with chronic liver diseases the concentration of these metabolites is significantly lower, and in patients with cirrhosis а considerable decrease of vitamin D metabolites is observed. The concentration of 25-hydroxyvitaпtin D and 1,25-dihydroxycholecalciferal didn't depend on the etiology of chronic hepatitis (there were no significant differences between groups of patients with viral hepatitis В and viral hepatitis С). Among patients with liver cirrhosis, the lowest levels of 25-hydroxyvitamin D and 1,25-dihydroxycholecalciferal were revealed in patients with alcoholic liver cirrhosis and under the decompensation process (Child-Pugh С). The discovered changes of vitamin D metabolites concentration indicate their involvement in the structural and functional bone disorder, particularly, in the development of osteoporosis. |
Type: | Text |
Publication type: | Стаття |
URI: | https://dspace.uzhnu.edu.ua/jspui/handle/lib/47746 |
Appears in Collections: | Науковий вісник УжНУ Серія: Медицина. Випуск 19 2003 |
Files in This Item:
File | Description | Size | Format | |
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МЕТАБОЛІТИ ВІТАМІНУ D У ХВОРИХ.pdf | 4.16 MB | Adobe PDF | View/Open |
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