Вплив небівололу на стан ренін-ангіотензин-альдостеронової системи та показники добової екскреції катехоламінів і рівень артеріального тиску у хворих на гіпертонічну хворобу

Abstract

31 patients with ischemia and complicated hypertension from which 15 patients with а mild form and 16 patients with moderate form of essential hypertension were studied for influence of nebivolol оn the state of rennin-angiotensin-aldesteron and sympathetic adrenalin systems as well as for the arterial pressure level during the course of medical treatment. The investigations showed that the prescription of nebivolol in а dose of 5mg daily to the patients with а moderate essential hypertension form and in а dose of 2.5 mg to the patients with а mild essential hypertension form resulted in significant reduction of daily catecholamine excretion. The indicated changes were followed bу stabilization of arterial pressure in patients with mild essential hypertension form and significant reduction in patients with moderate essential hypertension form.