Стан цитокінового профілю у дітей в приступному періоді бронхіальної астми в процесі валкіон-терапії

Abstract

With the method of immunoenzymoanalyses were inspected 56 children at the age of 5,5 to 14 years old in assault period of bronchial asthma. Тhе normal size of cytokines established in 16 healthy children. The complex treatment with using of the Valkion­therapy promoted normalization of the level IL-la (р<О,001), what point out to decrease of inflammatory process in the organism. There were marked too а positive dynamic in the production of cytokin-antagonist IL-4 (р<О,001) and IF-y (р<О,001) which have influence in the formation of lg Е. Children whose had got only traditional treatment marked the tendentious to positive shift levels IL-la (р<О,001), IL-4 (р<О,001), IF-y (р<О,001), but the normalization of these indexes did not come.