Передопераційна інтратуморальна термохіміотерапія при комбінованому лікуванні хворих на рак легені

Abstract

57 patients with lung cancer were administered transthoracic intratumor chemotherapy. Among them 27 patients received it simultaniously with hyperthermia and 30 patients without hyperthermia. After it 55 patients underwent radical surgery. Preoperative transthoracic intratumor chemotherapy, while increasing the concentration of cytostatic in the tumor has an expressed antiblastomic effect, does not cause а general toxicity and is well tolerated bу the host. Preoperative tтansthoracic intratumor chemotherapy leads to а significant devitalization of tumor cells before surgery, improves ablastic of surgery and does not complicate radical surgery and its postoperative period. This approach is well tolerated and results in major tumor response and allow to prolonged survival tim