Breast cancer

Abstract

Breast cancer is the most common cancer cases among female and 2nd most common cancer related death between females .it is a malignancy originating from breast tissue from ductal or lobular origin Prevalence is increasing, due to increased incidence and improvements in treatment outcomes. In most Western countries, the mortality rate has decreased in recent years, especially in younger age groups, because of improved treatment and earlier detection and screening programs. Gender and age play an important role in risk factors of breast cancer as well as family history, about a quarter of breast cancers occurring before age 50, and about 5% under age of 35, while the majority of cases occurs in ages > 50 years. Clinically breast cancer can be localized (limited to the breast), locally advanced, or metastatic breast cancer, which should be very well evaluated by right diagnostic staging, pathological diagnosis and to know the intrinsic subtype of breast cancer in order to offer right therapeutic plan and to get better treatment outcome.