Сlinical evaluation of effectiveness of application of photoactive disinfection in the treatment of localized periodontitis in children

Abstract

Laser technology opens a new promising direction in the treatment of periodontal disease. The antibacterial effect of the red diode laser is an important aspect of its multifactorial effect on biological systems. This effect of laser radiation in combination with its unique biostimulating properties can be used for selective inhibition of pathogenic microflora sensitized by drugs activated by laser light of relatively low power. Given that in the pathogenesis of periodontal disease, the infectious factor is crucial, the relevance of studying aspects of photodynamic therapy may become in the near future a real alternative to traditional methods of antibacterial action. The main goal of the study was to increase the effectiveness of treatment of localized forms of periodontitis in children of Transcarpathia the method of photodynamic therapy. The study included the treatment of localized forms of periodontitis in 117 children in the Upper Tysa region aged 12 to 15 years. Real-time polymerase chain reaction (PCR) was used to study saliva samples and the contents of periodontal pockets to detect species-specific DNA fragments of Streptococcus oralis, Streptococcus sanguis, Streptococcus sobrinus, Porphyromonas gingivalis, Treponema denticola. Analysis of oral biotope contamination by periodontal pathogens before and after treatment allowed to evaluate the effectiveness of periodontitis treatment. The effectiveness of combination treatment (antimicrobial topical therapy and exposure to red diode laser “Fotosan 630”), accompanied by regression of inflammatory reactions in periodontal tissues, reduction of total relative tissue contamination with periodontopathogenic microorganisms Streptococcus oralis, Streptococconascophycus sanguiscoiscus improving the clinical course of periodontitis.