Сучасні аспекти патогенезу, діагностики і лікування гострої кишкової непрохідності

Abstract

Experiment was perfoпned оп 26 unbreeded dogs. Bacteriologic investigations and electronic microscopy of intestinal mucous and parenchimatous organs were undertaken after model of acute intestinal obstruction (АЮ). Results of manage-ment of АЮ in 425 operated patients were analyzed. In experiment we observed colonization of pathogenic microorganismspredominantly in proximal small intestine with break ofmucous barrier that lead to the development ofmultiple organic fail ure in АЮ. Four stages of АЮ were assigned: І st stage - compensation, 2nd - subcompensation, 3rd - decompensation 4th - po/yorganic insufficiency. Such classification had peпnitted to unify the initial state estimation as well as ofpostoperativecourse, to differential the aµproach to complex treatment of patients.