Комплексне лікування перфоративних пілородуоденальних виразок з урахуванням гелікобактеріозу та стану кислотності шлунка

Abstract

The main theme contains analysis of the problem of Helicobacter pylori infection diagnosis and treatment in patients with perforated pyloroduodenal ulcers. The high Ievel of Helicobacter pylori infectivity and severe degree prevalence, as well as the correlative bond between infectivity degree and morphologic changes of perforated peptic ulcers, were established. The diagnostic and medical algorithm elaborated and incorporated in practice, which includes intraoperative diagnosis of Helico­bacter pylori infection presence bу two methods parallely (rapid urease test and smears-imprints cytologic analyse), differentiational prescription of eradication and antisecretory therapy in postoperative period with follow-up control of Helicobacter pylori eradication and stomach acidity. The complex treatment conduction with Helicobacter pylori eradication and acid suppression in patients with perforated pyloroduodenal ulcers solve to reduce essentialy relapsing level in long-term period after operation and improve an imme­diate and long-term results of urgent operations.