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Title: | DISCRETE LABORATORY AND MORPHOMETRIC MARKERS OF ATHEROSCLEROTIC LESIONS OF LOWER EXTREMITY VESSELS |
Other Titles: | DISCRETE LABORATORY AND MORPHOMETRIC MARKERS OF ATHEROSCLEROTIC LESIONS OF LOWER EXTREMITY VESSELS |
Authors: | Горленко, Олеся Михайлівна Горленко, Федір Вікторович Студеняк, В.М. Прилипко, Б.М. |
Keywords: | : patients, obliterating atherosclerosis of lower extremity vessels, endothelium, hyperhomocysteinemia, morphometry |
Issue Date: | 2020 |
Publisher: | © Wydawnictwo Aluna |
Citation: | Olesya M. Horlenko, Viktoriya M. Studenyak, Fedir V. Horlenko, Lyubomyra B. Prylypko SHEI «UZHHOROD NATIONAL UNIVERSITY», UZHHOROD, UKRAINE |
Series/Report no.: | Wiadomości Lekarskie 2020, tom LXXIII, nr 3;с. 561-564 |
Abstract: | The aim: To investigate discrete laboratory and morphometric features of atherosclerotic lesions in patients with chronic ischemia of the lower extremities (CILE). Materials and methods:The examined contingent consisted of 47 patients (age 56.32 ± 1.09 years) diagnosed with obliterating atherosclerosis of the lower extremities. The study included determination of levels of Homocysteine, Folic acid, C protein, quantitative determination of circulating Endothelial cells (DEC) in blood plasma, and morphometric study of DEC. Results: Protein C levels are within the reference values (0.97 ± 0.12 mg / l. In 37 (78.7%) patients Hypoacidofoliemia (<3.0 mmol / l) was observed. Homocysteine levels were clearly elevated in all patients. In the vast majority Hyperhomocysteinemia mild form (91.5%) was observed. The number of DEC in patients was -3.22 ± 0.39x105 /l and after compression –6.12 ± 0.21x105 /l Conclusions: Protein C levels were within the reference values (0.97 ± 0.12 mg / l); Folic acid levels in the vast majority (37 patients, 78.7%) were <3.0 mmol /l. Blood plasma Homocysteine levels were clearly elevated in all patients. The mild form of Hyperhomocysteinemia (91.5%). was observed in the vast majorityThe number of DEC in patients was -3.22 ± 0.39x105 and after compression –6.12 ± 0.21x105 /l, which confirmed the presence of the endothelial dysfunction. |
Type: | Text |
Publication type: | Стаття |
URI: | https://dspace.uzhnu.edu.ua/jspui/handle/lib/61044 |
Appears in Collections: | Наукові публікації кафедри педіатрії з дитячими інфекційними хворобами |
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File | Description | Size | Format | |
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DISCRETE LABORATORY AND MORPHOMETRIC MARKERS.pdf | 178.56 kB | Adobe PDF | View/Open |
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