Сlinical characteristics of the course of coronary heart disease with stable tension stenocardia in comorbidity with non-alcoholic steatohepatitis

Abstract

The diseases of the hepatobiliary system significantly aggravate the course of coronary heart disease, in particular, this applies to non-alcoholic steatohepatitis. Therefore, an important problem of current medicine is the study of common pathogenetic mechanisms of the development of this combined pathology. The aim of the work was to determine the features of the clinical course of coronary heart disease with stable tension angina in combination with non-alcoholic steatohepatitis depending on metabolic factors. 145 patients with coronary heart disease in combination with non-alcoholic steatohepatitis and 100 patients with coronary heart disesase without non-alcoholic steatohepatitis were examined. The clinical symptoms were characterized by the non-specificity of signs in relation to fatty liver damage. The clinical course of coronary heart disease in the presence of non-alcoholic steatohepatitis depends on the number of metabolic factors. In patients with coronary heart disease in combination with non-alcoholic steatohepatitis and metabolic risk factors, atrial fibrillation and the left or right branches of the bundle branch block are significantly more often registered than in patients with coronary heart disease without non-alcoholic steatohepatitis. The patients with coronary heart disease in the presence of non-alcoholic steatohepatitis and metabolic risk factors require hospitalization with a greater number of bed-days than patients with coronary heart disease without metabolic factors.