Preparation of Bisthiourea and 5-Amino-4-benzoyl-1,2,4-triazol-3-thione Complexes of Copper (II), Nickel and Zinc and its biological evolution.

Abstract

Novel Cu(II), Ni(II) and Zn(II) complexes that have N-({2- [(allylamino)carbonothioyl]hydrazino}carbonothioyl)benzamide, 5-allylamino-4-benzoyl-2,4- dihydro-3H-1,2,4-triazole-3-thione and 3-benzoyl-6-bromo-3,5,6,7-tetrahydro[1,2,4]triazolo[1,5- a]pyrimidine-2(1H)-thione moieties have been synthesized. All complexes were prepared by same technique due to interaction of ligands and corresponding metal (molar ratio 3:1) in boiling 95% water ethanol solution during 5 minutes. All these new compounds have been characterized by elemental analysis and various spectroscopic methods (IR, 1H, 13C NMR), and particularly for Ni(L1)2 by X-ray crystal structure determination. In addition, the possibility of biological evolution of obtained compound is shown.